Dokumentasjon om ketaminbehandling

Ketamin mot depresjon er et felt i utvikling, og vi å holde oss oppdatert på relatert litteratur og vitenskapelige studier. Vi har organisert et omfattende sett med kilder nedenfor, inkludert populære nyhetsartikler, viktige medisinske publikasjoner, systematiske oversikter og mer generelle ressurser.

Ketamine i nyhetsmedier

• The New Yorker: Ketamine Therapy Is Going Mainstream. Are We Ready?
• Elemental: Ketamine Is Revealing a New Understanding of Depression and the Brain
• Psychology Today: IV Ketamine for Treatment-Resistant Depression
• Gizmodo: More Than Just a Trip: Why Does Ketamine Work for Depression When Nothing Else Does?
• The New York Times: I Was Paralyzed by Severe Depression. Then Came Ketamine.

Societal consensus statements

• 2022 Updated US Guidelines for Treating MDD, Annals of Internal Medicine 2022
• A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders, JAMA Psychiatry 2017
• Intravenous Ketamine for Adults With Treatment-Resistant Depression or Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines, The Canadian Journal of Psychiatry 2021

Ketaminbehandling og depresjon

Systematic Reviews and Meta-Analyses

• Real-world effectiveness of ketamine in treatment-resistant depression: A systematic review & meta-analysis, Journal of Psychiatric Research, 2022
• Efficacy of ketamine for major depressive episodes at 2, 4, and 6-weeks post-treatment: A meta-analysis, Psychopharmacology 2021
• Neurocognitive effects of ketamine and esketamine for Treatment-Resistant Major Depressive Disorder: A systematic review, Harvard Review of Psychiatry 2021
• Comparative efficacy of racemic ketamine and esketamine for depression: A systematic review and meta-analysis, Journal of Affective Disorders 2021
• Registered clinical trials investigating ketamine for psychiatric disorders, Journal of Psychiatric Research 2020
• The relationship between subjective effects induced by a single dose of ketamine and treatment response in patients with Major Depressive Disorder: A systematic review, Journal of Affect Disorders 2020
• Leveraging neuroplasticity to enhance adaptive learning: The potential for synergistic somatic-behavioral treatment combinations to improve clinical outcomes in Depression, Biological Psychiatry 2019

Ketaminebehandling og depresjon

Nyheste artikkler

• Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial, Psychotherapy and Psychosomatics 2021
• Early symptomatic improvements as a predictor of response to repeated-dose intravenous ketamine, Progress in Neuro-Psychopharmacology and Biological Psychiatry 2021
• Cardiovascular effects of repeated subanaesthetic ketamine infusion in depression, Journal of Psychopharmacology 2020
• Antidepressant and Neurocognitive Effects of Serial Ketamine Administration Versus ECT in Depressed Patients, Journal of Psychiatric Research 2020
• Ketamine Normalizes Subgenual Cingulate Cortex Hyper-Activity in Depression, Neuropsychopharmacology 2020
• Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD), Nature 2018
• Maintenance Ketamine Therapy for Treatment-Resistant Depression, Journal of Clinical Psychopharmacology 2018

Forekomst av depresjon og bruk av antidepressiva

• National Institute of Mental Health: Review of Depression
• Efficacy and Effectiveness of Antidepressants: Current Status of Research

Historien om Ketamin

• Ketamine Wikipedia Entry
• Ketamine Manufacturer Data Sheet, Pfizer
• W.H.O. Fact Sheet, World Health Organization
• Ketamine - 50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms, Pharmacological Reports

Ketaminmisbruk

• A review of the non-medical use of ketamine, Journal of Psychoactive Drugs
• "The Ultimate Guide to Ketamine", The Third Wave (harm reduction network)
• DEA Fact Sheet on Ketamine, Drug Enforcement Agency

Ketamine og andre mental helse lidelser

Bipolar Disorder: Ketamine for bipolar depression: a systematic review, International Journal of Neuropsychopharmacology 2021

• Substance Abuse Disorder: Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review, Frontiers in Psychiatry 2018
• PTSD: Evidence for the beneficial effect of ketamine in the treatment of patients with post-traumatic stress disorder: A systematic review and meta-analysis.
• Journal of Cerebral Blood Flow & Metabolism, 2022
• Suicidal Thoughts: Ketamine for suicidal ideation in adults with psychiatric disorders: A systemic review and meta-analysis of treatment trials Au and Nz Journal of Psychiatry 2019
• Anxiety Disorder: Efficacy and safety of ketamine in the management of anxiety and anxiety spectrum disorders: a review of the literature, CNS Spectrums 2019
• Pain disorders: Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management, Regional Anesthesia and Pain Medicine 2018